A COMPARATIVE EVALUATION OF THE ACTION OF NOVEMBICHIN, HISTAMINE, AND CHICKEN YOLK ON THE DEVELOPMENT OF EXPERIMENTAL PLAGUE,

In single administration of novembichin and chicken yolk there was a considerable rise of the body sensitivity of albino mice to weakly virulent and avirulent Past. pestis strains i.e., under the effect of the preparations mentioned the animals life span was reduced more than two-fold and the possibility of isolating the Past. pestis culture increased 3-4 fold. The action of histamine in this respect was insignificant. Consequently, the administration of chicken egg yolk and novembichin may be successfully used for a more thorough investigation of the focus, detection of residual infectiousness and isolation of Past. pestis strains of low virulence. Author