STUDIES ON DISTRIBUTION OF ELAPINE VENOMS IN ANIMAL BODIES AFTER ENVENOMATION,

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Abstract:

The distribution of the venom of Bungarus multicinctus, its neurotoxins alpha-and beta Bungarotoxin and the venom of Naja naja atra in the animal bodies after envenomation was studied. No detectable amount of the unlabelled Bungarus-venom was found in the C. S. F. of rabbits injected intravenously with 1 mgkg 40 MLD of the venom. After I. V. injection of 10 mgkg, only a tiny amount of the venom up to 0.023 0.007 microgramsml was detected in the C. S. F., the highest C. S. F.plasma ratio being 1750 at 2 hr. after the injection. Author

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