ASCORBIC ACID, BIOLOGICAL FUNCTION AND CHEMISTRY.

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Abstract:

The objective of this work is to initiate a study on the biochemistry of ascorbic acid. Two major areas have been covered. a What are the sequence of events and chemical nature of the oxidation of ascorbic acid AsH2 to monodehydroascorbic acid AsH to dehydroascorbic acid dAs. b What are the metabolically active forms of vitamin C and their role on an enzymic level. Our progress in this work is detailed in three sections of this report 1 Study of Ascorbate Oxidation. 2 Synthesis of Tritium Labeled Ascorbates. 3 The Ascorbate Enzyme System. In addition, cooperative work on ascorbate assays has been done in connection with the Chemical Division of the Medical Research and Nutrition Laboratories of the Fitzsimons Army Hospital, Denver. Author

Author(s):
Bell, E. ; Levandoski, N. ; Tolbert, Bert M.
Author Organization(s):
COLORADO UNIV AT BOULDER DEPT OF CHEMISTRY
Descriptive Note:
Final rept.,
Supplementary Note:
Prepared in cooperation with Fitzsimons Medical Nutritional Lab., Denver, Colo.
Annotation:
Biological function and chemistry of ascorbic acid.
Pagination:
0012

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Contract/Grant Number(s):
DA49 193MD2611
 Subject Terms
Communities of Interest:
Biomedical
Descriptor(s):
(*ASCORBIC ACID, BIOCHEMISTRY), (*OXIDATION, ASCORBIC ACID), METABOLISM, SYNTHESIS(CHEMISTRY), INFRARED SPECTRA, MASS SPECTROSCOPY, NUCLEAR MAGNETIC RESONANCE, TRITIATED COMPOUNDS, MOLECULAR ISOMERISM, ATOMIC ORBITALS, LINE SPECTRA, PROTONS, ELECTRONS, TRANSPORT PROPERTIES, ENZYMES, ADENINE, NUCLEOTIDES, NICOTINIC ACID, AMIDES, LABELED SUBSTANCES
Keyword(s):
DOUBLET STATE, SINGLET STATE, TRIPLET STATE
Report Date:
1965 Jun 30