ANTIMICROBIAL SUBSTANCES IN SALIVA AND ORAL TISSUES
Abstract:
EV N PLASMA PROTEINS HAVE BEEN IDENTIFIED IMMUNOCHEMICALLY IN SALIVA AND PAROTID FLUID. Gamma globulin was determined quantitatively and its concentrations in both fluids were independent of the presence, in the subjects, of dental caries, periodontal disease or multiple myeloma. Analysis of the gamma-globulins revealed a large number of antibodies detectable by hemagglutination and bacterial agglutination but not by precipitation or complement fixation. A search for complement has been thw rted by anticomplementary effects of both oral fluids. The study of saliva sterilization has produced two simple techniques which reliably kill icroorganisms without significan ly altering ot r pro i co po s of saliva. Author