DID YOU KNOW? DTIC has over 3.5 million final reports on DoD funded research, development, test, and evaluation activities available to our registered users. Click
HERE to register or log in.
Accession Number:
AD1208070
Title:
Autonomic Dysfunction, Brain Blood Flow, and Cognitive Decline in Veterans with Gulf War Illness
Report Date:
2023-07-01
Abstract:
The incidence of multi-symptom illness or Gulf War Illness (GWI) in the Veterans deployed during the Gulf War is estimated to be 25-32 percent. The primary goal of this project is to examine cerebral blood flow responses to chemical and metabolic stress in Veterans with GWI compared with age and deployment-matched Veterans. We hypothesize that GWI is associated with both vascular dysfunction in the cerebral circulation and autonomic dysfunction. Participants will take part in a laboratory visit for autonomic function testing, and a magnetic resonance imaging scan (MRI) visit to determine brain structure and intracranial blood flow measurements at rest and in response to physiological stress. These experiments represent a novel and comprehensive approach and address fundamental and significant unresolved physiological questions in how GWI affects the human brain, with relevance to GWI symptoms.
Document Type:
Conference:
Journal:
Pages:
8
File Size:
0.26MB
W81XWH-19-1-0381
(W81XWH1910381);
Contracts:
Grants:
Distribution Statement:
Approved For Public Release
