The objective of this project is to identify the impact of stress and trauma on heterogeneity in lupus disease activity and symptoms, and the potential mediating role of sleep disturbances. The project addresses three aims: (1) Identify the association of current levels of stress and history of stressful and traumatic events with lupus symptoms and outcomes, both concurrently and longitudinally; (2) Identify current and longitudinal associations of sleep disturbances and changes in sleep disturbances with lupus health outcomes; and (3) Determine the relationship among stress/trauma, sleep disturbances and lupus symptoms and disease activity. To date, we have achieved the first two major tasks from the SOW projected to be completed in the first 6 months of the project: IRB approval from both the local IRB and HRPO, and development of the protocol, including interview protocol, manual of operations, and construction of database for entry of data. We had begun to recruit participants when the COVID-19 pandemic triggered a shut-down of research operations. We have now resumed with modified procedures, and have conducted 13 baseline assessments, with additional assessments scheduled.