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Accession Number:
AD1197264
Title:
Review of Skin and Cornea Laser-Induced Damage Thresholds from 1400 nm to 2000 nm and Broad-Spectrum Supra Threshold Effects
Report Date:
2021-06-30
Abstract:
Previous incarnations of dose response modeling have incorporated threshold-level damage endpoints at common laser wavelengths, but there is an increasing need to incorporate the full range of effects, those categorized as supra-threshold, over a broader wavelength region. This report reviews the published literature on threshold-level laser-induced damage to skin and cornea to highly-absorbed wavelengths, particularly in the region from 1400 to 2000 nm. Furthermore, it examines existing studies on laser induced supra-threshold effects in skin and cornea across a broader wavelength region. A result of this review is recognition of the paucity of supra-threshold studies of laser skin interaction, particularly in terms of dose correlations to skin burn degrees and ablation thresholds. While several corneal ablation threshold studies exist, there is not a consensus in the literature on how to approach supra-threshold corneal damage in the injury region between the minimum visible lesion and ablation onset. We propose a sub-ablative "first degree" supra-threshold lesion metric, while designating the ablation onset as "second degree" supra-threshold.
Document Type:
Conference:
Journal:
Pages:
53
File Size:
2.15MB
FA8650-19-C-6024
(FA865019C6024);
Contracts:
Grants:
Distribution Statement:
Approved For Public Release
