Major Goals: (1) The proposed infrastructure is composed of three subnets that are interconnected, each of which allows both single-hop and multi-hop communications, which can support a variety of settings with dynamic spectrum detection and occupation in case of malicious interference and wireless jamming. Therefore, we will be able to collect very comprehensively, versatile data sets when spectrum sensing and scheduling information. (2) The proposed infrastructure is quite comprehensive and advanced in the sense that there are two co-existing networks: (i) the cognitive radio network operating over the TV white spectrum frequencies of 54-60 MHz, 76-88 MHz, 174-216 MHz, 470-608MHz, and 614-698 MHz , and (ii) The 4G cellular, Long Term Evolution (LTE) network operating on bands 12 and 17 of the 700MHz LTE spectrum. We will use an 8-node computing cluster, universal software radio peripheral (USRP) X300, LTE base station (BS), and LTE user equipment (UEs). Therefore, this prototype allows us to study inhomogeneous wireless networks and evaluate the vulnerability of different combinations. (3) The proposed infrastructure prototype is an open access system in that each wireless device is allowed to dynamically explore the spectrum under attacks and severe interference, achieving opportunistic communications in real settings rather than in theory or principle. To some extent, this infrastructure is a proof-of-concept platform, which enables us to practice a large body of research outcomes. Furthermore, this project will be used for research-related education, that is, undergraduate and graduate students will be involved in building the prototype, thus gaining experience through participating in the project.