Osteoarthritis (OA) is a chronic, degenerative, often crippling disease that primarily affects large weight-bearing joints. OA is most commonly linked to wear and tear of the joints from old age. In younger people, though, it arises from a significant joint injury, one that damages the bones and cartilage (post-traumatic osteoarthritis; PTOA). Indeed, OA one of the primary causes of disability among active duty soldiers and veterans. Despite the constant claims in the media, there is no drug or dietary supplement capable of slowing joint destruction in OA and although some drugs can ease OA joint pain, they can't stop the erosive biological processes.