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Accession Number:
AD1191297
Title:
A Novel Imaging Agent for Detecting and Monitoring Lupus Nephritis
Report Date:
2022-10-01
Abstract:
This is a project to develop methods for detecting and monitoring inflammation in patients with systemic lupus erythematosus (SLE) in order to non-invasively detect tissue inflammation. This method will allow clinicians to: 1) more accurately identify which patients with SLE need to be treated with immunosuppressive drugs, and 2) determine whether immunosuppressive treatment of these patients is effective. These imaging methods will provide the same information that can currently be obtained only by an invasive tissue biopsy. Because these imaging methods expose patients to very low levels of radiation, they can be repeated as needed to assess changes over time. These methods will directly improve the care of patients with SLE because an accurate method of monitoring tissue inflammation will reduce permanent organ damage by under-treatment of the disease while also reducing side effects caused by unnecessary treatment.
Document Type:
Conference:
Journal:
Pages:
7
File Size:
0.32MB
W81XWH-19-1-0717
(W81XWH1910717);
Contracts:
Grants:
Distribution Statement:
Approved For Public Release
