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Accession Number:

AD1190725

Title:

Genetics of Frontotemporal Degeneration in Diverse Populations

Author(s):

Author Organization(s):

Report Date:

2022-07-01

Abstract:

Genomic analyses in diverse populations of frontotemporal dementia patients are currently lacking. Here we present the first report on creation of a (Caribbean) Hispanic cohort through enrollment in the greater South Florida area and Puerto Rico as well as well the first genomic analyses using genotyping and whole genome sequencing approaches. Enrollment was delayed due to COVID-19 hesitancy but plans are in place to improve in the next reporting period. Further efforts to increase outreach are being developed. Preliminary analyses indicate good representation of diverse genetic ancestries in the dataset and no known FTD mutations in genes originally identified in European FTD patients were identified so far. Whole genome sequencing and genotyping on the full cohort is currently ongoing.

Pages:

11

File Size:

0.51MB

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Distribution Statement:

Approved For Public Release

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