DID YOU KNOW? DTIC has over 3.5 million final reports on DoD funded research, development, test, and evaluation activities available to our registered users. Click HERE
to register or log in.
Evaluation of Partial Flow Strategies in Hemorrhage and Traumatic Brain Injury with Endovascular Variable Aortic Control
Both iREBOA and pREBOA are partial flow strategies, building upon the success of REBOA (complete aortic occlusion) to achieve hemorrhage control and restore hemodynamics in patients with exsanguinating noncompressible truncal hemorrhage. These techniques aim to extend the duration of intervention and minimize ischemia to distal tissue beds prior to definitive surgical hemostasis, particularly in austere military environments. An ideal strategy balances hemodynamic stability to the heart, lungs and brain, while minimizing downstream ischemia. This is especially important in the context of traumatic brain injury (TBI), where brain hypoperfusion is known to result in worse neurologic outcomes. In preliminary studies, pREBOA promotes improved hemodynamic stability through continuous low level downstream blood flow, whereas iREBOA can result in pronounced hemodynamic shifts at the time of balloon deflation. We hypothesize that hemodynamic stability, cerebral perfusion and blood loss utilizing automated pREBOA will be superior to iREBOA.
Approved For Public Release