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Effects of Fluctuations in Oxygen Partial Pressure from Normoxia to Moderate Hyperoxia
Pilots in modern tactical aircraft breathe oxygen-enriched gas supplied by onboard oxygen generating systems (OBOGS). These may provide their maximum possible oxygen fraction at all times (nominally 94%), or, like that in the F-35, control the oxygen fraction at lower concentrations on a schedule based on altitude. The altitude-based schedules have a wide band of acceptable oxygen concentrations, and OBOGS that follow them may supply gas concentrations that fluctuate within the acceptable band. This IRB-approved study addressed a concern that unsteady oxygen partial pressure might be related to physiological episodes (PEs). Oxygen concentrations of 21% (air) and 35% were supplied on the ground to approximate operational conditions in which the inhaled partial pressures fluctuate by 15% from normoxia to slight hyperoxia at a cabin altitude of 8,000 feet.
Approved For Public Release