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Accession Number:

AD1155392

Title:

Targeting Diet-Microbiome Interactions in the Pathogenesis of Parkinson's Disease

Author(s):

Author Organization(s):

Report Date:

2021-09-01

Abstract:

The current project will analyze the gut microbiome and metabolites from PD patients and controls, and employ clinically relevant mouse models to determine how metabolites produced by the microbiome from dietary substrates affect motor symptoms. We propose to test whether directly regulating microbial metabolite profiles using "designer" dietary fibers and probiotics offers new avenues for ameliorating PD-like symptoms. During this reporting period 17 new human subjects were successfully recruited at this performance site.

Pages:

8

File Size:

0.40MB

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Identifiers:

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Distribution Statement:

Approved For Public Release

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