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Accession Number:
AD1155392
Title:
Targeting Diet-Microbiome Interactions in the Pathogenesis of Parkinson's Disease
Report Date:
2021-09-01
Abstract:
The current project will analyze the gut microbiome and metabolites from PD patients and controls, and employ clinically relevant mouse models to determine how metabolites produced by the microbiome from dietary substrates affect motor symptoms. We propose to test whether directly regulating microbial metabolite profiles using "designer" dietary fibers and probiotics offers new avenues for ameliorating PD-like symptoms. During this reporting period 17 new human subjects were successfully recruited at this performance site.
Document Type:
Conference:
Journal:
Pages:
8
File Size:
0.40MB
W81XWH-17-1-0587
(W81XWH1710587);
Contracts:
Grants:
Distribution Statement:
Approved For Public Release