DID YOU KNOW? DTIC has over 3.5 million final reports on DoD funded research, development, test, and evaluation activities available to our registered users. Click
HERE to register or log in.
Accession Number:
ADB274630
Title:
Estrogen Metabolism and Prostate Cancer Risk
Corporate Author:
STATE UNIV OF NEW YORK AT BUFFALO AMHERST
Report Date:
2001-04-01
Abstract:
Experimental evidence shows that estrogens are related to prostate cancer risk - In addition recent data suggest that 16 alpha hydroxilated estrogen metabolites, biologically strong estrogens, are associated with cancer risk, while Z-hydroxyisted metabolites, with lower estrogenic activity, are weakly related to this disease. This study analyzes the association of prostate cancer with estrogen metabolism in a population-based study conducted in Erie and Niagara Counties - the Protein Study - Data in 81 prostate cancer cases and 318 control subjects showed that a higher ratio of 2 hydroxyestrone to 16 alpha hydroxyestrone uses associated with a reduced risk of prostate cancer.
Descriptive Note:
Final rept. 1 Oct 1998-30 Mar 2001
Pages:
0050
Contract Number:
DAMD17-98-1-8559
File Size:
1.76MB
