FRANKLIN INST RESEARCH LABS ROCKVILLE MD SCIENCE INFORMATION SERVICES DEPT
This Problem Definition Study provides a literature review 113 references on occupational health hazards and environmental aspects of zinc chloride which is a major product of a smoke generated from HC hexachloroethane mixture for screening purposes and fire-fighting exercises. Included are physical and chemical properties, human and animal toxicity, effects on microorganisms, plants, and aquatic organisms, pharmacokinetics, fate in the environment, industrial safety standards and practices, and sampling and analysis methodology of zinc chloride. Environmental impact are discussed and recommendations for further studies are provided. Zinc chloride is hygroscopic and astringent and has been found to be toxic if inhaled at elevated concentrations or in enclosed spaces with inadequate ventilation. In occupational exposure, contact with the skin, eyes, or nose can cause severe burns. Ingestion of zinc chloride solutions can result in severe gastrointestinal ulceration. No evidence exists in the literature that zinc chloride is mutagenic. Injection of zinc chloride solutions into the yolk sacs of chicken eggs induced teratogenic effects. Teratogenic effects in other species have not been reported in the literature. There have been no reported cases of carcinogenicity due to zinc chloride exposure in humans.