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Accession Number:
ADA010237
Title:
Effects of Immunodepression on Antibody Binding Affinity.
Corporate Author:
CORNELL UNIV MEDICAL COLL NEW YORK
Report Date:
1975-05-31
Abstract:
There is a progressive increase in antibody affinity with time after immunization. Agents adjuvants which increase the magnitude of the immune response favor selection for high affinity antibody synthesis. Agents such as antigenic competition, cyclophosphamide, 6-mercaptopurine and anti-lymphocyte antiserum which nonspecifically depress the magnitude of the immune response tend to make selection for high affinity antibody synthesis proceed more slowly.
Descriptive Note:
Final rept. 1 Nov 71-1 Mar 75,
Pages:
0048
Contract Number:
N00014-70-A-0412-0002
File Size:
0.00MB
