DID YOU KNOW? DTIC has over 3.5 million final reports on DoD funded research, development, test, and evaluation activities available to our registered users. Click
HERE to register or log in.
Accession Number:
AD1096320
Title:
Cell Response Determinants in Laser-Induced Thermal Impacts
Corporate Author:
MEDIZINISCHES LASERZENTRUM LUEBECK Luebck Germany
Report Date:
2019-05-06
Abstract:
In contrast to exogenous determinant of cell death temperature x time following thermal stimulation, endogenous determinants turned out to be complexed and highly-regulated involving different proteins and molecules. Hsp70, which had been assumed to be one of the dominant determinants, also seems to be regulated by other different molecules such as VEGF and Thioredoxin, and calcium signaling appeared to be one of the key factors. We have established a real-time temperature measurement method for in-vitro cultures using optoacoustic technique. Using this method, mechanisms of temperature-resolved cell responses and determinants of subsequent cell functions could be investigated more in detail.
Descriptive Note:
Technical Report,16 Sep 2016,15 Dec 2018
Pages:
0033
Distribution Statement:
Approved For Public Release;
File Size:
2.49MB
