Oregon Health and Science University Portland United States
Control of balance requires complex integration of sensory and motor systems. Balance measurement is often over-simplified, preventing balance deficits from being identified and treated after mTBI. Our central hypothesis is that chronic balance deficits after mTBI result from impairments in central sensorimotor integration that may be helped by rehabilitation. This research has two objectives 1 to characterize balance deficits in people with mTBI, and 2 to use a novel auditory biofeedback device to improve measures central sensorimotor integration and balance control. Methods Aim I Balance Assessment mTBI patients with non-resolving balance deficits following injury and healthy control participants with no history of mTBI are currently being recruited and tested on a battery of vestibular, neurocognitive, and balance-related tests. Aim II Balance Rehabilitation mTBI patients a subgroup from Aim 1 are randomly allocated into a standard of care balance rehabilitation program either with, or without auditory biofeedback. Both groups receive rehabilitation two times per week for six weeks. All participants are tested at baseline during Aim I testing, and are tested again following the intervention period, and again 6 weeks later to determine retention of changes. Status We have screened a total of 155 subjects for participation in this study. Of those screened, a total of 108 subjects have been enrolled at both sites 51 chronic mTBI and 57 controls. 101 participants have completed baseline testing 47 chronic mTBI and 54 controls of the full protocol Aim 1. 27 of the chronic mTBI participants have fully completed rehabilitation and the 6 week post-rehabilitation testing, and 22 have completed the 12 week retention testing Aim 2. 10 out of the 10 control participants needed did return to complete the 6 week testing. Four chronic mTBI patients have been lost to follow up.