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Glutamate Neuroexcitotoxicity in GWI

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American University Washington United States

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The objective of the proposed research is to examine whether dietary exposure to food additives containing glutamate may be contributing to symptoms in Gulf War Illness GWI. The rationale for proposed study comes from data in the fibromyalgia field which suggests that reducing the consumption of dietary glutamate can reduce over-excitation in the nervous system, leading to symptom improvement. Since there is almost complete symptom overlap between fibromyalgia and GWI, it is of utmost importance to test this diet as a low-cost treatment option in GWI patients. Thus far, we have enrolled 16 subjects into the study and have 4 more people scheduled for their initial visit in the upcoming months. Overall, we are still on pace to recruit a total of 40 subjects in the timeline indicated in our SOW.

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Technical Report,01 Sep 2017,31 Aug 2018



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Approved For Public Release;

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