Accession Number:

AD1046206

Title:

Optimization of Delayed Tolerance Induction in Swine: A Clinically-Relevant Protocol for Immunosuppression-Free Vascularized Composite Allotransplantation

Personal Author(s):

Corporate Author:

Massachusetts General Hospital Boston United States

Report Date:

2017-10-01

Abstract:

This research project addresses the FY15 RTR Focus Areas of Understanding mechanisms of immune rejection and Immunomodulation approaches and mechanisms e.g., tolerance induction, chimerism. Tolerance of kidney allografts has been achieved in nonhuman primates NHPs using a the delayed period protocol, i.e. combination of post transplant non-myeloablative conditioning and donor bone marrow transplantation four months later DBMT.

Descriptive Note:

Technical Report,15 Sep 2016,14 Sep 2017

Pages:

0015

Descriptors:

Identifiers:

Subject Categories:

Communities Of Interest:

Distribution Statement:

Approved For Public Release;

File Size:

0.22MB

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