New York University School of Medicine New York United States
The goal of this proposal is to contribute as a network site to the continued development of infrastructure and operations of the Prostate Cancer Biorepository Network PCBN. The aim of the PCBN is to provide prostate researchers with high-quality, well-annotated biospecimens obtained in a systematic, reproducible fashion using optimized and standardized protocols. The PCBN is funded as a consortium of participating network sites that includes New York University, under the overall guidance of the coordinating center at Johns Hopkins. The NYU network site works collaboratively to contribute to the PCBN goals, through infrastructure development, biospecimen accrual and biospecimen specialized processing and disbursement to investigators. The NYU network site procures specimens from more than 3 facilities, from primary localized as well as metastatic and disproportionately affected prostate cancer patients and stores them to provide for high quality biospecimens. Additionally, clinical data including pathology and outcome data are annotated with the biospecimens. Specialized processing consists of tissue microarray design and construction. Biospecimens mainly tissue microarrays are disbursed to investigators approved through the PCBN. The combined efforts of the network site enables the PCBN consortium to successfully provide much sought after biospecimens for prostate cancer research.