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Accession Number:
AD1031776
Title:
Mitochondrial-Based Treatments that Prevent Post-Traumatic Osteoarthritis in a Translational Large Animal Intraarticular Fracture Survival Model
Corporate Author:
University of Iowa Iowa City United States
Report Date:
2016-09-01
Abstract:
The results of Specific Aims 1 and 2 in the rabbit model strongly supported choosing amobarbital and NAC for testing in the porcine intra-articular fracture model, which was proposed for Specific Aim 3. Data from Specific Aim 3 showed that acute treatment with amobarbital or NAC had significantly delayed the onset of arthritis in a clinically realistic model of PTOA.
Descriptive Note:
Technical Report,01 Sep 2015,31 Aug 2016
Pages:
0014
Distribution Statement:
Approved For Public Release;
File Size:
0.85MB