Accession Number:

AD1031776

Title:

Mitochondrial-Based Treatments that Prevent Post-Traumatic Osteoarthritis in a Translational Large Animal Intraarticular Fracture Survival Model

Personal Author(s):

Corporate Author:

University of Iowa Iowa City United States

Report Date:

2016-09-01

Abstract:

The results of Specific Aims 1 and 2 in the rabbit model strongly supported choosing amobarbital and NAC for testing in the porcine intra-articular fracture model, which was proposed for Specific Aim 3. Data from Specific Aim 3 showed that acute treatment with amobarbital or NAC had significantly delayed the onset of arthritis in a clinically realistic model of PTOA.

Descriptive Note:

Technical Report,01 Sep 2015,31 Aug 2016

Pages:

0014

Subject Categories:

Distribution Statement:

Approved For Public Release;

File Size:

0.85MB