This project achieves new 2D layered materials with chemically tunable properties. Two-dimensional 2D materials, such as graphene and layered chalcogenides, nitrides, and oxides, are an exciting new class of materials with extraordinary physical and chemical behaviors. These high-performance materials have the potential to enable an entire fleet of new applications ranging from electronics to photonics. This work develops innovative chemistries to make new types of 2D materials and to chemically alter these materials for specific application. Within the course of this work, we achieve i new opto-electronic silicon based 2D materials, ii new material coatings that can change color from transparent to blue chemically or with heat, and iii chemically tunable materials adaptable for a specific application such as electronics, optical devices, electrodes with chemically enabled conduction and transparency. Activities are integrated with in-situ fundamental investigation to synergistically develop a complete understanding in materials research.