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Cell-Surface Antigen Induced by Venezuelan Equine Encephalomyelitis Virus
FORT DETRICK FREDERICK MD
By immunofluorescence staining, a specific surface antigen induced by VEE virus was detected on L-929 cells. Induction of the antigen was dependent on viable virions. It was not, however, the consequence of viral protein coats deposited on cells. The formation of surface antigen was independent of viral RNA synthesis. It is suggested that the induction of cell surface antigen is coded by an early function of the viral genome.