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Candidiasis in Simians
FORT DETRICK FREDERICK MD
Candidiasis was diagnosed in six monkeys over a 10-month period. Most cases had been on antibiotic therapy for enterocolitis. Fungal invasion was seen in epithelium of the tongue, oral cavity, esophagus, and colon, and in hard keratin of the nails. Gross lesions of the anterior alimentary tract were either white patches or ulcers of the mucosa. Lesions of the colon consisted of a thick pseudomembrane that contained numerous Candida. The nails exhibited typical Candida onychomycosis. C. albicans was isolated from the two cases that were cultured. Tissue invasion by Candida blastospores and hyphae was histologically demonstrated in all cases.
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