A study of the behavior of red cells subjected to various chemical or enzymatic treatments demonstrates the presence of lipids in the cell site receptor of arborviruses. Inhibiting lipids are present in red cells, either agglutinable or non-agglutinable by arborviruses. The responsible fractions seem to be phosphatidylcholines. They are the same for all the viruses studied. The pH conditions for inhibition are analogous to those of hemagglutination. These facts suggest certain hypotheses on the actual nature of the red cell receptor site, and of the bonds between this site and the virions.
Trans. of Institut Pasteur, Paris. Annales (France) v108 p423-441 1965.