IMMUNOLOGICAL STUDIES ON CRYPTOCOCCOSIS. REPORT NO. 1. STUDIES ON THE EXTRACTION AND PURIFICATION METHODS OF THE POLYSACCHARIDE FRACTION FROM CRYPTOCOCCUS NEOFORMANS AND ON THE APPLICATION OF THE ANTIGEN FOR IMMUNOLOGICAL DIAGNOSIS OF EXPERIMENTAL CRYPTOCOCCOSIS,
To study immonological diagnosis of Cr. neoformans infection the polysaccharide fraction was extracted, purified from Cr. neoformans no. 2617 strain and used as an antigen for skin and precipitin reaction of the immunized rabbit. As a result of this experiment, the skin reaction was parallel to its precipitin reaction. Therefore, it is suggested that the polysaccharide fraction could be utilized as an antigen to diagnose human cryptococcosis infection. Author
Trans. of Nihon Saikingaku Zasshi (Japan) v15 n4 p444-448 1960.