DID YOU KNOW? DTIC has over 3.5 million final reports on DoD funded research, development, test, and evaluation activities available to our registered users. Click
HERE to register or log in.
Accession Number:
AD0837452
Title:
IMMUNOELECTROPHORETIC STUDIES ON PASTEURELLA PESTIS. III. THE SERUM ANTIBODIES OF RECOVERED PLAGUE PATIENTS
Corporate Author:
ARMY BIOLOGICAL LABS FREDERICK MD
Report Date:
1965-07-08
Abstract:
The serum of 11 patients suffering from pulmonary plague, and the serum of 25 patients suffering from bubonic plague, were studied. From the onset of the disease, a significant decrease of albumin and an increase of globulins, particularly gamma-globulins, was demonstrated. Three months after recovery, the electrophoretic pattern returned to normal. In sera of patients recovered from bubonic plague, the immunoelectrophoretic analysis showed the presence of a globulin migrating with the specific anti-plague gamma-globulin. This globulin is constituted, according to the moment of the disease, of a certain number of antibodies, corresponding to antigens determined on the P. pestis immunoelectrophoretic diagram. The lines i, c e seem to appear first then the lines b, j, k, then or according to the severity of the disease, the line b benign disease, j, k toxic infection. These lines disappear in an inverse order of their appearance, and all of them disappear 18 months after the end of the disease.
Supplementary Note:
Trans. of Institut Pasteur, Paris. Annales (France) v106 p236-248 1964.
Pages:
0015
Distribution Statement:
Availability: Document partially illegible.
File Size:
0.75MB
