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Accession Number:
AD0837175
Title:
THE DEVELOPMENT OF A LABORATORY MODEL FOR THE TRANSMISSION OF AFRICAN TRYPANOSOMIASIS,
Corporate Author:
WALTER REED ARMY INST OF RESEARCH WASHINGTON DC
Report Date:
1968-01-01
Abstract:
Glossina austeni can be readily infected with the polymorphic trypanosome, T. brucei Lugala I using guinea pigs as donor and recipient hosts and lop-eared rabbits as maintenance hosts. The age of the fly at the time of the infective meal is the most important factor in successful laboratory infections. Day old flies had a midgut infection rate of 27 while less than 1 of the older flies became infected. 3 of day old flies developed salivary gland infections. A complete cyclical transmission of T. brucei was demonstrated. Sufficient replicates of the infection procedures have been performed to indicate that this system should be a useful model for the study of African trypanosomiasis. Author
Pages:
0011
File Size:
0.00MB
