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MICROMETHOD OF SERUM NEUTRALIZATION OF POLIOMYELITIS. USE OF CELLULAR CULTURES ON MOLDED PLASTIC PLATES
FORT DETRICK FREDERICK MD
The importance of neutralizing antibody research in clinical or undetected poliomyelitis has been demonstrated in innumerable articles dealing with individual diagnoses or epidemiology or immunology of this affection. A test of serum neutralization whose technique is simple, rapid and sure-fire is described. The method includes the cultivation of detectable cells and the neutralization tests of the virus with the serum under study. The placement of the cells into the virus-serum mixture is made at the same time. Results are obtained within 48 hours.
Trans. from Institut Pasteur, Paris. Annales (France).
Approved for public release; distribution is unlimited. Document partially illegible.