WASHINGTON UNIV SEATTLE DEPT OF PREVENTIVE MEDICINE
Trachoma and inclusion conjunctivitis strains TRIC strains isolated on Taiwan and those received from laboratories throughout the world have been classified in the mouse toxicity prevention test into three major groups from ocular trachoma and three other major groups made up almost entirely of non-ocular trachoma TRIC strains eg. genital, inclusion conjunctivitis. Vaccine studies in monkeys have confirmed that protection with oil adjuvant preparations of purified vaccines can be obtained with homologous but not heterologous TRIC strains. TRIC agents and cytomegloviruses have been isolated from the genital tract of pregnant women on Taiwan. The significance of these isolations is under investigation. Studies have been continued on the growth of TRIC agents and tissue culture and the factors retarding continuous passage. Studies of congenital malformations on Taiwan now have a total sample base of more than 14,000 live births. Special investigations have been carried out of Downs syndrome, sex anomalies, and the de Lange syndrome. Author
Final rept., 1 Aug 65-31 Jul 66,
Prepared in cooperation with Naval Medical Research Unit No. 2, Taipei (Taiwan).