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Accession Number:
AD0623373
Title:
UPTAKE AND EXCHANGE OF CATECHOLAMINES IN RATE TISSUES AFTER ADMINISTRATION OF D- AND 1-ADRENALINE,
Corporate Author:
KAROLINSKA INSTITUTET STOCKHOLM (SWEDEN) DEPT OF PHYSIOLOGY
Report Date:
1964-06-30
Abstract:
The effect of d- and 1-adrenaline A on the catecholamine CA content of heart and liver of the rat was studied at various times following i.m. administration. It was observed that both isomers are readily taken up by these tissues and exchanged for the normal neurotransmitter, noradrenaline NA. The present experiments also present evidence for the uptake of both d- and 1-A into subcellular storage granules. The fall in the NA content of the organs was accompanied by an increased urinary excretion of NA. The present experiments also indicate that there is a slight steric preference for the storage in favor of the 1-isomer. Author
Supplementary Note:
Pub. in Acta Physiologica Scandinavica v63 p336-42 1965 (Copies available only to DDC users).
Pages:
0008
Contract Number:
AF EOAR31 64
Contract Number 2:
PHS NB04432 02
File Size:
0.00MB
