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Accession Number:
AD0481056
Title:
METABOLISM OF RICKETTSIAE AND RELATED MICROORGANISMS
Corporate Author:
NAVAL MEDICAL RESEARCH INST BETHESDA MD
Report Date:
1965-12-31
Abstract:
The pathway of glutamine utilization was investigated by thin layer chromatography. The accumulation of intermediates of the citric acid cycle from alpha-ketoglutarate to malate was demonstrated by incubating the microorganisms with small amounts of glutamine, labeled with 14C to a high degree of specificity, and large amounts of unlabeled intermediates. It was not possible, however, to demonstrate the accumulation of oxaloacetate or the tricarboxylic acids. The latter results can be attributed to the instability of oxaloacetate and the impermeability of the microorganisms to citrate.
Descriptive Note:
Progress summary rept. no. 7, 1 Oct-31 Dec 1965
Supplementary Note:
DOI: 10.21236/AD0481056
Pages:
0002
Contract Number:
AMC-18-064-93-63
File Size:
0.07MB
