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Accession Number:
AD0442409
Title:
STUDIES ON THE PURIFICATION OF VACCINIA VIRUS
Corporate Author:
ARMY BIOLOGICAL LABS FREDERICK MD
Report Date:
1964-05-01
Abstract:
Various methods are described and compared for removing extraneous matter from vaccinia virus suspensions. Of ten procedures tested, differential centrifugation and Freon extraction were the most successful. Both the partially purified suspensions and the dried products prepared from them had high virus titers in embryonated eggs and high infectivity for mice. Although both processes resulted in products with the same titers, the differentially centrifuged product was approximately tenfold more purified as shown by the percentage solids of the suspensions before freeze drying.
Descriptive Note:
Technical Manuscript
Supplementary Note:
DOI: 10.21236/AD0442409
Pages:
0015
Distribution Statement:
Approved for public release; distribution is unlimited.
File Size:
0.50MB
