Accession Number:

AD0271565

Title:

HAPTENIC PROPERTIES OF PARALYTIC SHELLFISH POISON

Personal Author(s):

Corporate Author:

ROBERT A TAFT SANITARY ENGINEERING CENTER CINCINNATI OH

Report Date:

1961-12-31

Abstract:

Serological studies on the immunogenic properties of biphenyl bridge conjugates of paralytic shellfish poison and protein PSP-azo-biphenyl- azoovalbumin indicate that antibodies produced by rabbits were directed against the protein portion of the molecule and that the PSP moiety did not possess haptenic properties. A method of coupling PSP to protein in an acid media through the intermediate action of formaldehyde is also described. Evidence is presented which suggests that the PSP is only slightly altered in this synthesis.

Descriptive Note:

Quarterly progress rept. no. 6, 1 Oct-31 Dec 1961

Supplementary Note:

Research conducted for the U.S. Army Biological Labs., Ft. Detrick, MD. DOI: 10.21236/AD0271565

Pages:

0021

Descriptors:

Subject Categories:

Communities Of Interest:

File Size:

0.65MB

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