Accession Number:

AD0265486

Title:

CUTANEOUS TOXICITY EVALUATION OF AIR FORCE DEVELOPMENT MATERIALS - IV

Corporate Author:

INDUSTRIAL BIOLOGY RESEARCH AND TESTING LABS INC PHILADELPHIA PA

Report Date:

1961-04-01

Abstract:

Twelve Air Force development materials were studied via the prophetic patch test method on laboratory animals and volunteer human subjects to determine the primary irritant effect and the sensitization index of these materials. These materials were also studied by the Shelanski repeated insult patch test method on human volunteers to determine the primary irritation effect, fatiguing effect, and sensitization index. The patch test studies with rabbits indicated that only one material, Alkyldecalin, was too severe a primary irritant to test on humans. Upon testing the remaining materials on humans, Diethylcyclohexane was found to be a severe primary irritant. All other materials were found to be safe to use in contact with the human skin.

Descriptive Note:

Rept. for Feb 1960-Jan 1961

Supplementary Note:

DOI: 10.21236/AD0265486

Pages:

0015

Communities Of Interest:

Distribution Statement:

Approved for public release; distribution is unlimited.

Contract Number:

AF 33(616)-6962

File Size:

0.60MB