Accession Number:

ADP019906

Title:

Vibrational Microspectroscopic Imaging: Spatial Resolution Enhancement

Descriptive Note:

Conference paper

Corporate Author:

NATIONALINSTITUTES OF HEALTH BETHESDA MD NATIONAL INST OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES

Report Date:

2004-01-01

Pagination or Media Count:

7.0

Abstract:

We propose a methodology for enhancing the diffraction limited spatial resolution attained in Raman and Fourier transform infrared microspectroscopic imaging techniques. Near-field scanning optical microscopy SNOM and spectroscopy employ apertureless and aperture approaches to provide ultra-high spatially resolved images at the nanometer level. In contrast, we employ conventional spectral acquisition schemes modified by spatial oversampling with the subsequent application of deconvolution techniques. As an example, this methodology is applied to flat samples using point illumination. Simulated data, assuming idealized sample concentration profiles, are presented together with experimental Raman microspectroscopic data from chemically and morphologically well-defined test samples. Intensity profiles determined using conventional mapping and imaging techniques are compared to those obtained by the probedeconvolution methodology.

Subject Categories:

  • Atomic and Molecular Physics and Spectroscopy
  • Optics

Distribution Statement:

APPROVED FOR PUBLIC RELEASE