Accession Number:

ADP019721

Title:

Selective Laser Sintering of Polycaprolactone Bone Tissue Engineering Scaffolds

Descriptive Note:

Conference paper

Corporate Author:

MICHIGAN UNIV ANN ARBOR

Report Date:

2005-01-01

Pagination or Media Count:

7.0

Abstract:

Present tissue engineering practice requires porous, bioresorbable scaffolds to serve as temporary 3D templates to guide cell attachment, differentiation, and proliferation. Recent research suggests that scaffold material and internal architecture significantly influence regenerate tissue structure and function. However, lack of versatile biomaterials processing methods have slowed progress towards fully testing these findings. Our research investigates using selective laser sintering SLS to fabricate bone tissue engineering scaffolds. Using SLS, we have fabricated polycaprolactone PCL and polycaprolactonetri-calcium phosphate composite scaffolds. We report on scaffold design and fabrication, mechanical property measurements, and structural characterization via optical microscopy and micro-computed tomography.

Subject Categories:

  • Polymer Chemistry
  • Fabrication Metallurgy

Distribution Statement:

APPROVED FOR PUBLIC RELEASE