Accession Number:

ADP019711

Title:

New Biological Labels Based on Functionalized YVO4:Eu Nanoparticles

Descriptive Note:

Conference paper

Corporate Author:

ECOLE POLYTECHNIQUE PALAISEAU (FRANCE)

Report Date:

2005-01-01

Pagination or Media Count:

6.0

Abstract:

Lanthanide-ion doped oxide YVO4Eu nanoparticles were synthesized as aqueous colloids and functionalized by a bioactive silane shell to be used as fluorescent biological labels. Nanoparticles functionalized with guanidinium groups were able to act as artificial toxins which specifically target Na channels. They were individually detectable in live cardiac myocytes. Functionalized oxide nanoparticles appear as a new interesting tool, especially attractive for long-term single-molecule tracking due to their photo-stability and long luminescence lifetime.

Subject Categories:

  • Inorganic Chemistry
  • Optics

Distribution Statement:

APPROVED FOR PUBLIC RELEASE