Accession Number:

ADP019694

Title:

Helical Rosette Nanotubes as a Potentially More Effective Orthopaedic Implant Material

Descriptive Note:

Conference paper

Corporate Author:

PURDUE UNIV LAFAYETTE IN

Report Date:

2005-01-01

Pagination or Media Count:

6.0

Abstract:

Organic nanotubes called helical rosette nanotubes HRN have been synthesized in this study for bone tissue engineering applications. They possess intriguing properties for various bionanotechnology applications since they can be designed to mimic the nanostructured constituent components in bone such as collagen fibers and hydroxyapatite Ca5PO4SUB 3OH which bone cells are naturally accustomed to interacting with. This is in contrast to currently used orthopaedic materials such as titanium which do not possess desirable nanometer surface roughness. The objective of this in vitro study was to determine bone-forming cell osteoblasts interactions on titanium coated with HRNs. Results of this study showed for the first time increased osteoblast adhesion on titanium coated with HRNs compared to those not coated with HRNs. In this manner, this study provided evidence that HRNs should be further considered for orthopaedic applications.

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE