Accession Number:
ADP013607
Title:
Oligonucleofide Imprinting in Aqueous Environment
Descriptive Note:
Conference paper
Corporate Author:
CALIFORNIA UNIV IRVINE DEPT OF CHEMISTRY
Personal Author(s):
Report Date:
2002-04-05
Pagination or Media Count:
8.0
Abstract:
The development of synthetic receptors that recognize nucleotide bases and their derivatives is an important area of research 1-3. Applications are envisioned in separation science, biosensors, drug therapy and genetic engineering. Previously in this laboratory, we have developed a molecularly imprinted synthetic receptor for 9-ethyladenine 9-EA. The network polymer has an affinity for adenine and its derivatives with an average association constant Ka of 75,000 M-1 in CHCl3.
Descriptors:
Subject Categories:
- Polymer Chemistry