Accession Number:

ADP013607

Title:

Oligonucleofide Imprinting in Aqueous Environment

Descriptive Note:

Conference paper

Corporate Author:

CALIFORNIA UNIV IRVINE DEPT OF CHEMISTRY

Personal Author(s):

Report Date:

2002-04-05

Pagination or Media Count:

8.0

Abstract:

The development of synthetic receptors that recognize nucleotide bases and their derivatives is an important area of research 1-3. Applications are envisioned in separation science, biosensors, drug therapy and genetic engineering. Previously in this laboratory, we have developed a molecularly imprinted synthetic receptor for 9-ethyladenine 9-EA. The network polymer has an affinity for adenine and its derivatives with an average association constant Ka of 75,000 M-1 in CHCl3.

Subject Categories:

  • Polymer Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE