Accession Number:

ADP011049

Title:

Medication for Motion Sickness

Descriptive Note:

Corporate Author:

ROYAL AIR FORCE FARNBOROUGH (UNITED KINGDOM) SCHOOL OF AVIATION MEDICINE

Personal Author(s):

Report Date:

2001-06-01

Pagination or Media Count:

4.0

Abstract:

Over the years many medicinal remedies have been proposed for the prevention of motion sickness. The number of drugs that has been tested is large, but relatively few are effective Table 1, and none can completely prevent the development of signs and symptoms in everyone in all provocative motion environments. When the motion is relatively mild and only 10 of the unmedicated population suffer from sickness, then use of a drug such as hyoscine scopolamine can increase protection so that all but 2 of the population remain symptom-free. But when the motion is of such severity and duration that 50 are sick when no drug is given, a large dose of hyoscine 1.0 mg still leaves 80 of the population unprotected. In life-rafts, sickness rates approaching 100 have been reported, so it is not surprising that a significant proportion of the occupants will still suffer from sea sickness even when the dose of drug given is sufficient to cause side-effects.

Subject Categories:

  • Stress Physiology
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE