Correlation of Serum Alpha sub 1 Antitrypsin with Cigarette Smoking and Pulmonary Function Status in Greek Pilots, for a Ten Year Period,
HELLENIC AIR FORCE TECHNICAL RESEARCH CENTER ATHENS (GREECE)
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Quantitative and mainly qualitative aberration of the Alpha 1 Antitrypsin a1AT a major constituent of the human antielastase screen, it strictly associated with the development of lung emphysema. Certain factors like cigarette smoking and environmental pollution may contribute to that. In this study we have correlated cigarette smoking with the serum a1AT concentration as well with the trend of the predicted values of Forced Vital Capacity FVC and lst Second Forced Expiratory Volume FEV1 over a ten years period. The study population consisted of 113 randomly selected male pilots, of the Greek Air force, being in flight duties grouped into non smokers n 49, age x 36-3 and effective smokers n64, age x38.4 smoking for more than ten years.
- Medicine and Medical Research