Development of a Paradigm to Assess Nutritive and Biochemical Substances in Humans: A Preliminary Report on the Effects of Tyrosine upon Altitude- and Cold-Induced Stress Responses
ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
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Tyrosine, a large neutral amino acid found in food, is the precursor for the catecholamine neurotransmitters dopamine and norepinephrine. Recent experiments have shown the behavior of animals given tyrosine is less impaired after stressful treatments than that of animals given placebo. Various environmental stressors are known to deplete central catecholamine stores and tyrosines positive behavioral effects in animals are associated with reversal of this neurochemical deficit. Therefore, we investigated whether tyrosine administration would reduce adverse behavioral and physiological effects in humans induced by two combined environmental stressors, hypoxia and cold.
- Stress Physiology