Animal Models for Assessing Male Reproductive Toxicity,
CINCINNATI UNIV OH DEPT OF ENVIRONMENTAL HEALTH
Pagination or Media Count:
The task of assessing reproductive risk in human populations is complicated by several factors. First, much of the information on sperm integrity i.e., sperm count, viability morphology has been obtained from suspected infertile or subfertile men. In studies of presumably healthy, fertile men, limited data are availability relating sperm integrity to sperm competence i.e., fertilizing ability, successful pregnancies. In such information is lacking for fertile, normal populations, it follows that the impact of environmental agents on sperm integrity or competence is even more obscure. Even assuming a defined relationship between sperm integrity and sperm competence, the study of environmentally-exposed human populations is fraught with problems.