Combination of Thermal Burns and Whole-Body Irradiation
BOSTON CITY HOSPITAL MA DEPT OF SURGERY
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Despite significant advances in medical technology such as recognition of physiological derangements, use of topical bactericidal agents, and improved surgical techniques, the care of the thermally burned patient remains a constant challenge to the medical profession. Review of the mortality and morbidity from burn centers across the United States indicates that mortality is usually associated with failures of resuscitation, a significant inhalation injury accompanied by pulmonary insufficiency, or one of the different manifestations of sepsis in the burn patient. Systemic sepsis in the burn patient that is not due to nosocomial infections or pulmonary injury is usually associated with a colonized or infected burn wound. Burn wound sepsis in some degree is present in most burn wounds beyond the 5th day regardless of topical therapy. However, burn wound sepsis manifests itself only if the bacterial count exceeds 100,000 organisms per gram of tissue.
- Medicine and Medical Research