Behavioral Toxicological Studies of Pesticides in Laboratory Rats,
ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD
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Behavioral testing procedures are still relatively new to the field of toxicology, but their use is rapidly growing. One of the principal reasons for their increasing popularity, and one which particularly bears on the Armys occupational health and safety programs, is that behavioral tests can often provide sensitive laboratory measures of low-level toxicity. While animals may appear to be normal after exposure to low concentrations of a potentially hazardous chemical, their performance in a given behavioral task may betray important changes in the way they perceive or operate in their environment. This paper discusses some of the behavioral data collected with two pesticide compounds in laboratory rats. Both sets of data provide interesting, although very different, examples of how the sensitivity of behavioral tests can provide useful information about toxicity.