Accession Number:

ADD018364

Title:

Antisense Oligonucleotides Directed against Human ELAM-I RNA.

Descriptive Note:

Patent, Filed 12 Oct 93, patented 17 Dec 96,

Corporate Author:

DEPARTMENT OF THE NAVY WASHINGTON DC

Report Date:

1996-12-17

Pagination or Media Count:

16.0

Abstract:

The present invention provides a method for the treatment of septic shock and inflammatory complications of shock. A process for selectively inhibiting the expression of the human ELAM-I mRNA transcript using at least one oligonucleotide which is substantially complementary to at least a portion of the ELAM-I gene is disclosed, as are composition comprising the oligonucleotide

Subject Categories:

  • Medicine and Medical Research
  • Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE