Accession Number:

ADD015304

Title:

Immuno-Dye Reagent and Assay for Detection of Endotoxin.

Descriptive Note:

Patent, Filed 29 Sep 89, patented 3 Mar 92,

Corporate Author:

DEPARTMENT OF THE NAVY WASHINGTON DC

Report Date:

1992-03-03

Pagination or Media Count:

4.0

Abstract:

A novel immuno-dye reagent capable of detecting the presence of endotoxin in samples has been developed. The immuno-dye reagent comprises a solution of new methylene blue and an anti-endotoxin monoclonal antibody specific to a selected endotoxin. The immuno-dye reagent can be used in an assay to detect endotoxin by reacting the immuno-dye reagent with an endotoxin suspect pH adjusted sample, under hydrophobic conditions. The immuno-dye reagent can also be used in any application where binding of endotoxin is crucial, such as purifying endotoxin-contaminated solutions.

Subject Categories:

  • Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE